You are here
Species
Flaviviridae
IUCN
NCBI
EOL Text
The Flaviviridae are a family of viruses that are primarily spread through arthropod vectors (mainly ticks and mosquitoes). The family gets its name from Yellow Fever virus, a type virus of Flaviviridae; flavus means yellow in Latin. (Yellow fever in turn was named because of its propensity to cause jaundice in victims.)[1]
Flaviviridae have monopartite, linear, single-stranded RNA genomes of positive polarity, 9.6 to 12.3 kilobase in length. The 5'-termini of flaviviruses carry a methylated nucleotide cap, while other members of this family are uncapped and encode an internal ribosome entry site. Virus particles are enveloped and spherical, about 40–60 nm in diameter.
Taxonomy[edit]
This family includes the following genera:
- Genus Flavivirus (type species Yellow fever virus, others include West Nile virus and Dengue Fever)—contains 67 identified human and animal viruses
- Genus Hepacivirus (type species Hepatitis C virus,[2] also includes GB virus B)
- Genus Pegivirus (includes GB virus A, GB virus C, and GB virus D)
- Genus Pestivirus (type species bovine viral diarrhea virus, others include classical swine fever or hog cholera)—contains viruses infecting non-human mammals
Clinical importance[edit]
Major diseases caused by the Flaviviridae family include:
- Dengue fever
- Japanese encephalitis
- Kyasanur Forest disease
- Murray Valley encephalitis
- St. Louis encephalitis
- Tick-borne encephalitis
- West Nile encephalitis
- Yellow fever
- Hepatitis C Virus Infection
References[edit]
- ^ "Flaviviridae". Microbe Wiki. Retrieved July 22, 2008.
- ^ Paula T, Pablo R, Eugenia V, Pablo B, Sabino P, José M et al. (2009). "New drug targets for hepatitis C and other Flaviviridae viruses". Infect Disord Drug Targets 9 (2): 133–47. doi:10.2174/187152609787847749. PMID 19275702.
License | http://creativecommons.org/licenses/by-sa/3.0/ |
Rights holder/Author | Wikipedia |
Source | http://en.wikipedia.org/w/index.php?title=Flaviviridae&oldid=643366631 |